Spire has recently announced Ergo, which is the first mechanical gaming keyboard in the TKL (tenkeyless) form factor to offer a custom ergonomic layout that is said to reduce strain during long sessions.
The keyboard is designed to split the QWERTY keyset into two halves that are angled, with vital keys placed in the gap between the two halves. The keyboard is actually split into two halves, each made to sit right under your thumbs.
Spire has also moved around many important keys so they are not where you would expect them. The keyboard offers full RGB illumination and features Cherry MX key switches. It is priced at $80.