ASRock has already built the first LGA2011v2 Mini-ITX motherboard. This allowed you to have a very impressive small form factor system, although you only had the ability to have dual-channel memory. Now they have done it, their latest motherboard, the EPC612D4I, gives you quad channel memory on the Mini-ITX form factor!
This motherboard is not made for the mainstream though, it is a server-grade motherboard. The board achieves quad-channel memory support by using smaller DDR4 SO-DIMM slots instead of the standard DIMM slots. Since this is an enterprise board it supports Xeon E5-1600 V3 and E5-2600 V2 processors.
Being a server-grade motherboard there are not overclocking features, it is based off the Intel C612 chipset. There is a single PCI-Express 3.0 x16 slot. There is even on-board video, driven by the ASPEED AST2400 remote management chipset. Output comes by way of a D-Sub and supports resolutions of up to 2048 x 1536. This chip is actually wired to its own dedicated Gigabit Ethernet connection, and there are two more Gigabit Ethernet connections powered by the Intel i210 and i217LM controllers. For storage you have four SATA 6GB/s ports. The board has official support for Windows 2012 R2/2008 R2 SP1, SuSE Server 11 SP3, RHEL 6.5, CentOS 6.5, Fedora 19, Ubuntu 12.10, and FreeBSD 9.2.