There are a few ways to overlock the X99S MPower. The easiest way would be to enable OC Genie. This can be done by powering off your system and pressing the OC Genie button towards the bottom of the board then powering your system on. Doing this it brought our Core i7-5960X from 3.0 GHz up to 3.7 GHz.
Of course we knew we could do better than that and went into the BIOS and did some tweaking. To start I set the CPU Core Voltage to 1.4V, the CPU Ring Voltage to 1.2V and the VCCIN Voltage to 2.0V. Then I started moving the CPU multiplier up until the system was not stable.
I ended up crashing at 4.5 GHz, so I moved down to 4.4 GHz for a stable overclock. That is a 1.4 GHz overclock, not bad at all!
If we compare that to the other X99 motherboards we have tested with this processor you can see that it is on par with the EVGA X99 Micro as far as overclocking potential.